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The tumors possibly connected to pediatric gene therapies make me sad. Babies.
The need-to-know this morning
- Vir Biotechnology said monthly injections of two experimental medicines reduced hepatitis D virus to undetectable levels in 44% of patients compared to none of the patients who received delayed treatment with the same regimen. The result achieved the primary goal of a Phase 3 study.
- Zura Bio said its experimental antibody tibulizumab failed to improve the symptoms of hidradenitis suppurativa, an inflammatory skin condition, compared to a placebo in a mid-stage study.
- Roivant said Lisraya generated $31 million in sales in the five weeks since it was approved to treat dermatomyositis.
- Argenx is acquiring privately held Unnatural Products, a medicinal chemistry company that specializes in the discovery of protein-based drugs.
Why two heart trials should puncture AI drug discovery enthusiasm
Before anyone promises that AI will cure every disease, consider what happened the last time a shiny new tool was supposed to make drug development more predictable. At the American Heart Association meeting, two big trials came up empty.
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